Pure Bioscience's silver dihydrogen citrate (SDC) antimicrobial was shown to be effective against biofilm, according to preliminary results of in vitro laboratory tests conducted at the University of Medicine & Dentistry of New Jersey.
SDC is a new molecular entity, developed and patented worldwide by Pure Bioscience. It is an electrolytically generated source of stabilized ionic silver in liquid form that provides superior antimicrobial efficacy with residual protection while mitigating bacterial resistance, according to the company.
"We have used SDC against single species biofilms of Aggregatibacter actinomycetemcomitans, a causative agent in localized aggressive periodontitis, and S. epidermidis, a pathogen associated with hospital settings," said researcher Narayanan Ramasubbu, PhD, an associate professor in the department of oral biology. "Our results show that these bacteria in the biofilm state are killed within minutes at 30 ppm [parts per million] of SDC."
SDC killed biofilm bacteria and also inhibited the biofilm formation at levels as low as 1.5 ppm in a citrate-containing medium, Ramasubbu added.
